Dr. Sean M Bagshaw

Dr. Bagshaw is an intensive care physician, the Scientific Director for the Critical Care Strategic Clinical Network, Professor and Chair of the Department of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, and a Canada Research Chair in Critical Care Nephrology. He received his M.D. from the University of Calgary and went on to complete subspecialty training in Internal Medicine and Critical Care, both at the University of Calgary, He also completed an MSc in Epidemiology with the Department of Community Health Sciences at the University of Calgary. He further completed post-doctoral training in Critical Care Nephrology at the Austin Hospital in Melbourne, Australia. His research bridges clinical trials, health services research and operations management across several themes in critically ill patients, including acute kidney injury, vulnerable and frail patients, and ICU organization.


Position/Title: Professor and Chair / Scientific Director

Institution: Faculty of Medicine and Dentistry, University of Alberta / Alberta Health Services

Department: Department of Critical Care Medicine

Email: bagshaw@ualberta.ca

Link to Institutional Profile: https://www.ualberta.ca/medicine/about/people/sean-bagshaw

Curriculum Vitae: Download

Areas of Expertise: Critical Care, Nephrology, Frailty, ICU Organization, Quality of Care, Health Services Research, Clinical Trials

Names of Current Grants/Project Titles:

2019-2021; A Pragmatic, Stepped-wedge, Cluster-randomized, Registry-embedded Implementation Trial of an Evidence- informed Change in Practice from Liberal to Conservative 02 Therapy in Critically III Mechanically Ventilated Patients (OXY-ICU); SPOR – Pragmatic Clinical Trial Demonstration Project Grant $100,000; PI: Sean Bagshaw

2018-2020: A Pragmatic Cluster, Randomized, Crossover, Registry-Embedded Clinical Trial of Proton Pump Inhibitors vs. Histamine-2 Receptor Blockers for Stress Ulcer Prophylaxis Therapy in the Intensive Care Unit (PEPTIC Study).

2015 - 2021: STandard versus Accelerated initiation of Renal Replacement Therapy in Acute Kidney Injury (STARRT-AKI): A Multi-National Randomized Clinical Trial. Funded by CIHR, NHMRC, and HRCNZ.

2016 - 2018: Clinical Frailty Scale Score Implementation into a Provincial Bedside Clinical Information System (eCritical). Funding by Canadian Frailty Network.

2014 – 2018: Identifying and Evaluating Intensive Care Unit Capacity Strain in Alberta. Funded by Partnership for Research and Innovation in the Health System from Alberta Innovates – Health Solutions.

Select Publications:

The STARRT-AKI Investigators (Bagshaw SM and Wald R – Principal Investigators). Timing of Initiation of Renal-Replacement Therapy in Acute Kidney Injury. N Engl J Med 2020; 383:240-251.